Table 2. Univariate and Multivariate analysis of clinical parameters in relation to overall survival.

	Univariate		Multivariate
Variables	HR (95%CI)	P	R (95%CI)	P
miR-26a expression	3.732 (1.814–6.421)	0.031*	3.461(1.331–5.364)	0.013*
Age at diagnosis	1.515 (0.574–1.842)	0.583	1.215(0.609–2.074)	0.437
Gender	1.936 (0.762–2.452)	0.678	1.548 (0.652–2.115)	0.547
Clinical stage at diagnosis	3.547 (1.427–4.416)	0.015*	3.112 (1.268–3.709)	<0.001*
Invasion depth	2.615 (0.894–3.431)	0.106	2.314 (0.852–2.472)	0.0891
Lymph vessel infiltration	3.462 (2.134–5.383)	0.031*	2.953 (2.141–3.458)	0.007*
Distant metastasis	2.784 (1.487–4.125)	0.017*	3.456 (1.424–6.135)	0.008*
Differentiation	4.193 (2.216–7.146)	0.002*	2.986 (1.897–4.116)	0.017*

CI: confidence interval; HR: hazard ratio

^*Significant relation of clinical factors with overall survival