Table 1.
Screening | Psychiatric interview | Entry to clinical trial | 1-2 weeks | 1 month | 2 months | 3 months | 4 months | 5 months | 6 months | |
---|---|---|---|---|---|---|---|---|---|---|
Informed Consent | X | X | X | |||||||
Inclusion/exclusion criteria fulfilled | X | X | X | |||||||
Demographics | X | |||||||||
Co-morbid conditions (self-report) | X | |||||||||
Charlson Co-morbidity Index [29] | X | X | X | X | X | X | X | |||
Brief psychiatric history | X | |||||||||
BDI-II [23] | X | X | ||||||||
PHQ-9 [26] | X | X | X | X | X | X | X | X | ||
P4 Suicidality Screener [33] | X | X | X | X | ||||||
Psychiatric Assessment | X | X | X | X | X | |||||
Montgomery- Asberg Depression Rating Scale [25] | X | X | X | X | ||||||
Mini International Neuropsychiatric Interview [24] | X | |||||||||
List of medications | X | X | X | X | X | X | X | |||
Description of dialysis treatment | X | X | X | X | X | X | X | |||
Mid-week pre and post dialysis blood pressure | X | X | X | X | X | X | X | X | ||
Dry weight | X | X | X | X | X | X | X | X | ||
Adherence to dialysis treatment | X | X | X | X | X | X | X | X | ||
Interdialytic weight gain | X | X | X | X | X | X | X | X | ||
Urine volume per 24 h | X | |||||||||
Dialysis adequacy Kt/V | X | X | X | X | X | X | X | X | ||
Dialysis time | X | X | X | X | X | X | X | X | ||
Urea & electrolytesa | X | X | X | X | X | X | X | X | ||
Full blood countb | X | X | X | X | X | X | X | X | ||
Liver function testsc | X | X | X | X | X | X | X | |||
Electrocardiogram | X | X | X | X | ||||||
IMP review | X | X | X | X | X | X | ||||
Drug compliance | X | X | X | X | X | X | X | |||
Sertraline Plasma blood test | X | |||||||||
Baseline assessment of signs and symptoms | X | |||||||||
Adverse events | X | X | X | X | X | X | X | |||
Kidney Disease QoL questionnaire [30] | X | X | X | X | ||||||
Euroqol EQ 5D questionnaire [22, 31] | X | X | X | X | ||||||
Clinical Global Impression Severity Scale [28] | X | X | X | X | ||||||
Clinical Global Impression Improvement Scale [28] | X | X | X |
aUrea, Creatinine, Calcium, Sodium, Potassium and Bicarbonate
bHaemoglobin, White blood cell count and platelets
cBilirubin, Albumin, Alanine transaminase (ALT), Aspartate transaminase (AST), Aspartate Aminotransferase, Calcium, Phosphate and C-Reactive Protein