Table 5.
Univariate Cox proportional hazard regression analysis for time to biochemical progression according to tumor expression of IAPs and caspases
| p | HR (95 % CI) | p | HR (95 % CI) | ||
|---|---|---|---|---|---|
| cIAP1/2 | 0.931 | 0.970 (0.485-1.938) | Procaspase-8 | 0.962 | 1.018 (0.487-2.129) |
| cIAP2 | 0.646 | 1.176 (0.588-2.351) | Cleaved caspase-8 | 0.222 | 0.653 (0.330-1.294) |
| NAIP | 0.543 | 0.811 (0.412-1.596) | Procaspase-3 | 0.005* | 0.260 (0.100-0.672) |
| Survivin | 0.108 | 1.831 (0.875-3.834) | Cleaved caspase-3 | 0.002* | 0.327 (0.161-0.662) |
| XIAP | 0.055 | 0.460 (0.208-1.016) | Caspase-7 | 0.435 | 1.310 (0.665-2.579) |
| Procaspase-9 | 0.936 | 1.029 (0.515-2.055) |
Abbreviations: CI confidence interval, HR hazard ratio. Bold values indicate statistical significance. *p < 0.05