Boubaker 2012.
| Clinical features and settings | Inclusion period: n.r. Patient population: 357 patients with newly diagnosed high risk stage 4 neuroblastoma (HR‐NBL1/SIOPEN trial). Consecutive series: n.r. Diagnostic work‐up: n.r. Time spans symptoms‐index test, symptoms‐reference standard and index test‐reference standard: n.r. Treatment between index test‐reference standard: n.r. |
| Participants | Included patients: 357 patients with newly diagnosed high risk stage 4 neuroblastoma. Median age at first diagnosis: n.r. Sex distribution: n.r. INSS stage: n.r. |
| Study design | Cohort study with patients from the (HR‐NBL1/SIOPEN trial). N.r. whether the study was retrospective or prospective. |
| Target condition and reference standard(s) | Target condition: newly diagnosed high risk stage 4 neuroblastoma. Reference standard: n.r. |
| Index and comparator tests | Index test: ¹²³I‐MIBG scintigraphy. Radiofarmacon: ¹²³I‐MIBG. Dose: n.r. Collimator: n.r. Matrix: n.r. Acquisition protocol: n.r. Acquisition time: n.r. Acquisition duration: n.r. Interfering medication: not reported. Thyroid prophylaxis: not reported. Positive test result: skeletal ¹²³I‐MIBG uptake. Number and expertise of observers: eight nuclear medicine experts in four groups. Interobserver concordance: n.r. |
| Follow‐up | n.r.; some patients were followed for approximately five years. |
| Notes | This study has not been published in full‐text (as of December 2012), but has been presented at the ANR conference 2012. Results not reported for ¹²³I‐MIBG scans at first diagnosis separately from the ¹²³I‐MIBG scans during follow‐up. We could not get in contact with the study authors. |