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. 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2

Hervas 2001.

Clinical features and settings Study period: n.r.
Patient population: 20 patients with neuroblastoma with 47 ¹²³I‐MIBG scans.
Consecutive series: n.r.
Diagnostic work‐up: n.r.
Time spans between symptoms and index test, between symptoms and reference standard and between index test and reference standard: n.r.
Treatment between index test and reference standard: n.r.
Participants Included patients: children with newly diagnosed neuroblastoma.
Median age: n.r.; mean age: 4.4 years (SD 2.45).
Sex distribution: 12 boys (60%), 8 girls (40%).
INSS stage: two stage 1, three stage 2, three stage 3 and 12 stage 4.
Study design Retrospective.
Target condition and reference standard(s) Target condition: neuroblastoma.
Reference standard: histology.
Index and comparator tests Index test: ¹²³I‐MIBG scintigraphy.
Radiofarmacon: ¹²³I‐MIBG.
Dose: 3,7 MBq/Kg.
Collimator: low energy.
Matrix: n.r.
Acquisition protocol: thorax, abdomen, lateral skull, and occasionally the extremities.
Acquisition time: 3, 24, and 48 hours after injection.
Acquisition duration: n.r.
Interfering medication: n.r.
Thyroid prophylaxis: n.r,
Positive test result: when abnormal foci were observed (adrenal or extradrenals, or both) with increased uptake.
Number and expertise of observers: n.r.
Interobserver concordance: n.r.
Follow‐up n.r.
Notes Results n.r. for 20 patients with neuroblastoma at diagnosis separately from those during treatment.
We could not get into contact with the authors.