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. 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2

Moschogiannis 2011.

Clinical features and settings Study period: 2009 to 2010.
Patient population: 99 patients with suspected neuroblastoma with¹²³I‐MIBG scans.
Consecutive series: n.r.
Time spans between symptoms and index test, between symptoms and reference standard and between index test and reference standard: n.r.
Treatment between index test and reference standard: n.r.
Participants Included patients: 32 children with suspected neuroblastoma and a ¹²³I‐MIBG scan at diagnosis.
Median age: n.r. for these 32 included patients; for all 99 patients:range of 1 month to 8 years.
Sex distribution: n.r. for these 32 included patients; for all 99 patients: 52 boys (53%), 47 girls (47%).
INSS stage: n.r.
Study design Cohort study. N.r. whether the study was retrospective or prospective.
Target condition and reference standard(s) Target condition: newly diagnosed neuroblastoma.
Reference standard: n.r.
Index and comparator tests Index test: ¹²³I‐MIBG scintigraphy.
Radiofarmacon: ¹²³I‐MIBG.
Dose: n.r.
Collimator: n.r.
Matrix: n.r.
Acquisition protocol: planar and SPECT images; a subtraction technique was applied (a kidney's image using 99mTc‐DMSA subtracted from the ¹²³I‐MIBG scan, achieving a better localization of the adrenal medulla as well as a more exact determination of adrenal uptake).
Acquisition time: 24 hours after injection.
Acquisition duration: n.r.
SPECT: n.r.
Interfering medication: n.r.
Thyroid prophylaxis: stable iodide.
Positive test result: pathological uptake.
Number and expertise of observers: n.r.
Interobserver concordance: n.r.
Follow‐up n.r.
Notes Not published in full‐text (as of December 2012), but presented at the EANM conference 2011.
Results n.r. for ¹²³I‐MIBG scans at first diagnosis separately from the ¹²³I‐MIBG scans during follow‐up.
Contact information of the authors: not available.