Skip to main content
. 2015 Oct 14;172(20):4959–4969. doi: 10.1111/bph.13265

Figure 2.

Figure 2

Acute angiotensin (ANG) II stimulation alters NECA‐induced responses in MAs from WT mice. (A) Control tracing. (B) NECA‐induced responses after ANG II (10 nM) stimulation (bottom line represents baseline, and upper line shows stable contraction to PE). (C) Summarizes quantification of NECA‐induced responses in control and ANG II‐stimulated MAs. (D) Graph shows that responses of MAs to a series of increasing concentrations of NECA were comparable. (E) Effect of losartan (1 μM, 10 min) on NECA‐induced altered responses after ANG II stimulation. The graph shows that losartan pre‐treatment completely blocked altered responses to NECA after ANG II stimulation. Asterisk (*) indicates p < 0.05 compared with control, and number sign (#) denotes p < 0.05 compared with losartan‐treated response.