Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ERK1/2 inhibition reduces angiotensin (ANG) II‐induced vasoconstriction and altered responses to NECA in MAs from WT mice. (A) PD98059 (1 μM), an ERK1/2 inhibitor, significantly reduced ANG II (10 nM)‐induced vasoconstrictions (control n = 10, PD98059 n= 6; *P < 0.05 compared with control). (B) Altered response to NECA after ANG II stimulation was also blocked by PD98059. *P < 0.05 compared with control NECA response, and #P < 0.05 compared with response after PD98059 treatment.
