Table 1.

Baseline and follow-up characteristics of the study subjects

	Baseline			After one year
	Improvement	Same or worsening	P value	Improvement	Same or worsening	P value
Age (years)	52.18 ± 8.2	53.8 ± 7.6	NS
Sex (male/female)(%)	46.2 vs 53.8	42.2 vs 57.8	NS
Group (control/intervention)	51.8/48.2	48/52	NS
Weight (kg)	79.1 ± 13.6a	81.7 ± 15.2b	NS	76.6±12.8a	80.6 ± 14.7b	0.03
BMI (Kg/m2)	30.2 ± 4.7a	31.3 ± 5.2b	NS	29.2±4.3a	30.9 ± 5.2b	0.01
WHR	0.94 ± 0.08	0.93 ± 0.08	NS	0.94±0.08	0.94 ± 0.07	NS
Fasting glucose (mmol/l)	5.92 ± 0.74c	6.0 ± 1.0d	NS	5.27±0.6c	6.08 ± 0.93d	<0.001
Alcohol consumption (%) Every day	27.4	31.1	NS
Smoking (%) Yes	29.2	23.8	NS
Physical activity (%)			0.001
Slight	33.8	47.1
Moderate	44.6	47.1
Intense	21.5	5.8
Mediterranean Diet Pattern (%)	53.1	47.4	NS
Global methylation (%5mC)	64.7 ± 2.4	63.9 ± 1.7	0.003

^aP value before vs. after intervention < 0.001.

^bP value before vs. after intervention < 0.001.

^cP value before vs. after intervention = 0.001.

^dP value before vs. after intervention = NS.