Table 2.

Association of LINE-1 methylation with carbohydrate metabolism disorders after unadjusted and adjusted logistic regression models

	OR	IC 95%	P value
Model 1
Age (years)	1.01	0.98–1.05	NS
Sex (male vs. female)	0.85	0.48–1.52	NS
BMI (Kg/m2)	1.01	0.96–1.07	NS
Group (control vs. intervention)	0.85	0.46–1.58	NS
Model 2a
Physical activity
Slight vs intense	4.74	1.61–13.90	0.005
Moderate vs intense	3.14	1.11–8.88	0.031
Model 3b
LINE-1 methylation levels (%5mC)	0.81	0.68–0.97	0.021

Dependent variable: metabolic status after one year (0: improvement, 1: same or worsening).

^aAdjusted for age, gender, baseline BMI, and group.

^bAdjusted for age, gender, group, BMI, and physical activity at baseline.