Overview of X-chromosome cytosine modification data (A) Distribution of X-chromosome cytosine modification levels in females (purple) and males (green). (B) Distribution of X-chromosome cytosine modification levels in CEU (blue) and YRI (red) female LCLs. (C) Principal Component Analysis of X-chromosome cytosine modification levels in LCLs, diffuse large B cell lymphomas (DLBCL), haematopoietic stem/progenitor cells (HSC/prog), and pre-B cell acute lymphoblastic leukemia (pre-B ALL) samples. (D) Correlation matrix of X-chromosome cytosine modification levels in LCLs, DLBCL, HSC/progenitor cells, and pre-B cell ALL samples.