FIG 1.

Schematic depiction of the subject cohorts analyzed in this study. (A) The number of subjects in each cohort is indicated in the corresponding box. Multiple cohorts were grouped together for analysis. Subjects who spontaneously cleared their C. trachomatis (CT) infection or were not infected despite repeated exposure were grouped in the effective immune response cohort, subjects who exhibited persistent C. trachomatis infection and/or progressed to PID were grouped in the ineffective immune response, and subjects with documented C. trachomatis exposure that progressed to TFI or were able to complete a pregnancy successfully were grouped in a fertility cohort. A group of subjects, presumably nonexposed to C. trachomatis, were also recruited as naive controls. (B) Numbers and percentages of subject samples screened for T cell responses (CD4⁺ and CD8⁺) for each cohort.