Table 1.

Characteristics of Samples

	Controls	FD	IBS
Number (females)	56 (32)	32 (26)	49 (21)
Age (yr)	51.4 ± 2.2	53.8 ± 3.0	40.9 ± 2.3a,c
Number of subtypes of IBS
Diarrhea	-	-	28
Constipation	-	-	9
Mixed	-	-	11
Unclassified	-	-	1
Number of subtypes of FD
PDS	-	25	-
EPS	-	7	-
Number of types of non-GI controls
Annual health check	31	-	-
Mild hypertension/hyperlipidemia	25	-	-
IBS-SSS total score	30 ± 7	192 ± 16a	252 ± 16a,c
Abdominal pain severity	1 ± 1	21 ± 4a	45 ± 4a,c
Abdominal pain frequency	0.1 ± 0.0	2.7 ± 0.6a	4.3 ± 0.5a,b
Abdominal bloating	2 ± 1	42 ± 6a	38 ± 5a
Bowel dissatisfaction	18 ± 4	55 ± 6a	65 ± 4a
Interference with life	8 ± 3	46 ± 6a	62 ± 4a

Characteristics of each group were shown.

FD, functional dyspepsia; IBS, irritable bowel syndrome; PDS, postprandial distress syndrome; EPS, epigastric pain syndrome; GI, gastrointestinal; IBS-SSS, IBS symptom severity scale.

Data were expressed as mean ± SEM,

^aP < 0.01 vs Controls;

^bP < 0.05,

^cP < 0.01 vs FD.