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Extent of conservation of interface location and interaction pattern in core and rim interface residues. (a) Extent of core and rim interface residues to show conserved interface location. (b) Extent of core and rim residues that have conserved residue type and conserved interface location have been shown for all the 20 residue types. (c) Extent of core–core, core–rim, and rim–rim interactions to show conserved interaction pattern.
