Table 1.
Clinical features of all patients at baseline.
| Clinical features | Value |
|---|---|
| Male:Female | 198:101 |
| Age, year mean (range) | 62.5 (40–85) |
| Mean follow up, months (range) | 66 (12–120) |
| Mean total bilirubin value at diagnosis (mean ± SD) | 16 ± 5.5 |
| Recurrent episodes of acute cholangitis, n (%) | 245 (81.9) |
| Recent right flank pain alone, n (%) | 54 (18.1) |
| Intrahepatic stone classification (Tsunoda) n (%): | |
| Class I | 66 (22.1) |
| Class II | 92 (30.7) |
| Class III | 91 (30.4) |
| Class IV | 50 (16.7) |
| Previous cholecystectomy, n (%) | 91 (31.4) |
| Previous liver transplant, n (%) | 42 (14.4) |
| Previous pancreatic or gastrointestinal surgical resection, n (%) | 86 (29.6) |
| Liver resection, n (%) | 71 (24.6) |
| Presence of strictures, n (%) | 141 (47.1) |
| Benign, n (%) | 76 (54) |
| Malignant, n (%) | 65 (46) |
| Associated disease at diagnosis: | |
| Biliary cirrhosis, n (%) | 30 (10) |
| Cholangiocarcinoma, n (%) | 29 (9.7) |
| Liver primary/secondary neoplasms, n (%) | 35 (11.7) |
SD, standard deviation.