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. 2015 Sep 14;4(11):1333–1343. doi: 10.5966/sctm.2014-0273

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Figure 4. — THI supplementation enhanced functional recovery after myocardial infarction. Echocardiographic analysis of left ventricular function and remodeling parameters. Treatment with THI enhanced cardiac recovery after acute myocardial infarction induced by left coronary artery ligation. Left ventricular ejection fraction (A), left ventricular end-systolic diameter (B) and volume (C), left ventricular end-diastolic volume (D), posterior wall (E), and infarct wall thickness (F) were assessed before infarction (baseline) and 48 hours and 5 weeks after myocardial infarction in vehicle-control (n = 12) and THI-treated (n = 10) mice. Values are presented as mean ± SEM (∗, p < .05 compared with controls). Abbreviations: LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; THI, tetrahydroxybutylimidazole.