Table 1.

Site-specific antibody-drug conjugation on N-glycan of Fc does not affect the antibody binding activity to FcγRI and FcγRIIIa

	ka[1/Ms]		kd[1/s]		KD[M]
Antibody	FcγRI	FcγRIIIa	FcγRI	FcγRIIIa	FcγRI	FcγRIIIa
m860 IgG1	4.5E+4	1.1E+4	0.001007	0.01608	2.2E-8	1.5E-6
m860ADC	4.4E+4	0.9E+4	0.001078	0.01752	2.5E-8	1.9E-6
Control IgG1	7.6E+4	2.2E+4	0.001372	0.01484	1.8E-8	6.7E-7