Table 1.
Antimicrobial activity of Fl-PRPRPL-5 against clinical isolates of Staphylococcus aureus
| Staphylococcus strain name
|
Origin | Molecular typing
|
Phenotypic properties | MIC/MBC (µM) | ||
|---|---|---|---|---|---|---|
| NARSA ID | Alternate designation | SCCmec type | spa type | |||
| NRS382 | USA100 | US | II | TJMBMDMGMK | Resistant to ciprofloxacin, clindamycin, erythromycin, and methicillin | 16/16 |
| NRS383 | USA200 | US | II | WGKAKAOMQQQ | Resistant to ciprofloxacin, clindamycin, erythromycin, gentamicin, and methicillin | 16/16 |
| NRS384 | USA300 | US | IV | YHGFMBQBLO | Resistant to erythromycin, methicillin, and tetracycline | 16/16 |
| NRS386 | USA700 | US | IV | UJGFMGGM | Resistant to erythromycin and methicillin | 16/16 |
| NRS107 | – | US | – | YHGGFMBQBLQ | Resistant to methicillin and mupirocin | 16/16 |
| VRSA5 | – | US | II | TJMBMDMGMK | Resistant to vancomycin | 8/8 |
| S. aureus | – | – | – | – | Biofilm-producing clinical isolate | 16/16 |
| ATCC 6538 | ||||||
| S. epidermidis | NRS-101 | US | – | – | Biofilm-producing clinical isolate; resistant to methicillin and gentamicin | 8/16 |
Abbreviations: NARSA, Network on Antimicrobial Resistance in Staphylococcus aureus; ID, identification; MIC, minimum inhibitory concentration; MBC, minimum bactericidal concentration; ATCC, American Type Culture Collection; spa, staphylococcal protein A; SCC, staphylococcal cassette chromosome; –, not available.