Table 1.
PDADMAC dose required for optimal flocculation performance at varying solids content in the cell broth. Cell broth was diluted with cell culture media to adjust the solids content. Optimal flocculation performance is the combination of the shortest flocculent settling period and with an optical clarity of less than 40 NTU
| Normalized Flocculent Dosing To: |
||||
|---|---|---|---|---|
| Solids | Flocculent Dose (g/L) | Volume (g/L Cell Broth) | Solids (mg/L Solids) | Total Cells (pg/TC) |
| 10.8% | 0.6 | 0.6 | 5.6 | 48.5 |
| 16.1% | 1.0 | 1.0 | 6.2 | 43.6 |
| 20.5% | 1.3 | 1.3 | 6.3 | 44.2 |
| 25.4% | 1.8 | 1.8 | 7.9 | 43.5 |
| Mean Dose | 1.2 | 6.5 | 45.0 | |
| % sM | ± 68.5% | ± 24.1% | ± 8.4% | |