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. 2015 Jan 20;16(2):244–252. doi: 10.1080/15384047.2014.1002346

Figure 3.

Figure 3.

Effect of FIH-1 overexpression on proliferation, migration, invasion of LOVO and SW1116 cells. (A) Overexpression of FIH-1 had significant effect on decreasing proliferation rate of both LOVO and SW1116 cell lines. (B) Wound closure was delayed in cells transfected with FIH-1 overexpression plasmidbitorfunctional assays. We 31 can directly regulate FIH-1 expression in both CRC tissue and cell lines. Next we examined th as compared with negative control in 18 h time points in both types of CRC cells. (C) Representative fields of migration (up) or invasion (down) cells on the membrane were on the left. Average migration or invasion cell number per field was on the right. The migration or invasion cell number of LOVO or SW1116 transfected with FIH-1 overexpression plasmidbitorfunctional assays. We 31 can directly regulate FIH-1 expression in both CRC tissue and cell lines. Next we examined th was drastically decreased. (D) The number of clones of LOVO or SW1116 transfected with FIH-1 overexpression plasmid was fewer than that of control cells.