Figure 5.
FIH-1 controls the tumor growth of LOVO xenografts in vivo. (A) Overexpression of FIH-1 strikingly decreased the growth of LOVO cells xenografted in nude mice. (B) The tumors were significantly bigger in control group than those in treated group. (C) The tumors were significantly heavier in control group than those in treated group. (D) The protein expression levels of FIH-1, GLUT-1, and VEGF in the subcutaneous tumor tissues collected from control and treated groups were detected by IHC.