Figure 2.

The burden of metastatic disease in the liver does not correlate with CTC count as determined by the CellSearch method. Shown are CT scans of the abdomen from 2 patients (A and B) with diffuse colorectal cancer with hepatic metastases and high baseline CTC numbers. CT scans were performed before initiation of chemotherapy (baseline). The scans in panel C provide illustrative examples of the observed inter-patient heterogeneity from 4 patients. The numbers in black depict the ratio of total liver volume: volume of disease free liver, and the numbers in red depict the mean CTC count from replicates +/− standard error of the mean.