Table 1.
A partial list of overexpressed proteins identified in gastric adenocarcinoma
Novel proteins found to be overexpressed in gastric adenocarcinoma | ||||
---|---|---|---|---|
Gene symbol | Protein | Function | Fold-change | |
CAMKK2 | Calcium/calmodulin-dependent protein kinase kinase 2 | Plays a role in calcium/calmodulin-dependent signaling cascade | 7.0 | |
CNN2 | Calponin-2 | Functions in the structural organization of actin filaments | 2.7 | |
PRELP | Prolargin | Anchors basement membrane to underlying connective tissue | 2.6 | |
FLNA | Filamin-A | Involved in cytoskeletal remodeling | 2.0 | |
Overexpressed proteins that were previously reported in gastric adenocarcinoma | ||||
Gene symbol | Protein | Function | Fold-change | Citation |
TAGLN | Transgelin | Involved in actin cross linking | 3.4 | Huang et al, 200835 |
BGN | Biglycan | Involved in reassembly of collagen filaments and muscle generation | 2.4 | Wang et al, 201137 |
HSPB1 | Heat shock protein β-1 | Involved in stress resistance and organization of actin filaments | 2.3 | Ren et al, 200636; Ryu et al, 200353 |
S100A8 | Protein S100-A8 | Involved in cell cycle progression and differentiation | 2.1 | Yong et al, 200743 |
S100A6 | Protein S100-A6 | Involved in cell cycle progression and differentiation | 2.0 | Wang et al, 201042 |