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. 2015 Mar 10;16(2):336–345. doi: 10.4161/15384047.2014.972264

Table 1.

A partial list of overexpressed proteins identified in gastric adenocarcinoma

Novel proteins found to be overexpressed in gastric adenocarcinoma
Gene symbol Protein Function Fold-change  
 CAMKK2 Calcium/calmodulin-dependent protein kinase kinase 2 Plays a role in calcium/calmodulin-dependent signaling cascade 7.0  
 CNN2 Calponin-2 Functions in the structural organization of actin filaments 2.7  
 PRELP Prolargin Anchors basement membrane to underlying connective tissue 2.6  
 FLNA Filamin-A Involved in cytoskeletal remodeling 2.0  
Overexpressed proteins that were previously reported in gastric adenocarcinoma
Gene symbol Protein Function Fold-change Citation
 TAGLN Transgelin Involved in actin cross linking 3.4 Huang et al, 200835
 BGN Biglycan Involved in reassembly of collagen filaments and muscle generation 2.4 Wang et al, 201137
 HSPB1 Heat shock protein β-1 Involved in stress resistance and organization of actin filaments 2.3 Ren et al, 200636; Ryu et al, 200353
 S100A8 Protein S100-A8 Involved in cell cycle progression and differentiation 2.1 Yong et al, 200743
 S100A6 Protein S100-A6 Involved in cell cycle progression and differentiation 2.0 Wang et al, 201042