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. 2015 Oct 19;9:5697–5704. doi: 10.2147/DDDT.S89410

Figure 2.

Figure 2

Differences in gene expression between parental and PHA665752-resistant SNU-5 xenografts by RNA-Seq.

Notes: (A) Parental and PHA665752-resistant SNU-5 tumor tissues were resected from xenografts and the differences in the gene expression level were compared using RNA-Seq. (B) Validation of the genes expression between parental and PHA665752-resistant SNU-5 xenografts by qRT-PCR. RNA had previously been isolated from parental and PHA665752-resistant SNU-5 tumor tissues and was reverse transcribed to cDNA. The gene expression was validated by qRT-PCR and GAPDH gene was used as a reference gene. Mean ± SD, n=3. **P<0.01 vs parental SNU-5 tumor tissues.

Abbreviations: qRT-PCR, quantitative real-time PCR; PCR, polymerase chain reaction; SD, standard deviation.