Table 3.

Multivariate survival analyses (proportional hazards method) for patients with OSCC

Variable	Multivariate survival analysis
	Hazard ratio	95% CI	p-value
Gender (male, female)	1.627	(0.591, 4.479)	0.346
Age (≤60, >60)	0.998	(0.383, 2.611)	0.699
Primary site	1.033	(0.244, 4.366)	0.565
Tumor size (T1,T2, T3-T4)	1.380	(0.672, 2.834)	0.380
Pathological grade (I, II, III)	1.150	(0.613, 2.160)	0.363
Local recurrence (No, Yes)	0.953	(0.573, 1.652)	0.532
Cervical nodal metastasis (N0, N+)	2.412	(1.431, 4.562)	0.034
Distant metastasis (NO, Yes)	2.536	(1.843, 5.231)	0.043
Clinical stage (I-II, III-IV)	1.504	(0.649, 3.227)	0.611
PKM2 expression (low, high)	3.118	(1.445, 5.082)	0.028

Note: The numbers in bold indicate statistical significance.