Table 5.
Association of demographic, clinicopathological and p53 expression with overall survival using Cox's multivariate regression analysis (n = 120)
| Predictors | Odds ratio (OR) (95% CI) | p value |
|---|---|---|
| Age (yrs): ≤50 >50 |
Ref 1.39 (0.94–2.07) | 0.101 |
| Sex: Female Male |
Ref 1.01 (0.60–1.70) | 0.959 |
| PS: Good Poor |
Ref 0.80 (0.52–1.22) | 0.301 |
| Lesion site: Buccal mucosa Other sites |
Ref 0.79 (0.52–1.20) | 0.266 |
| Tumor size: T2 + T3 T4 |
Ref 1.48 (0.75–2.90) | 0.255 |
| Node metastasis : N0 N1 + N2 |
Ref 0.85 (0.56–1.29) | 0.437 |
| Stage: III IV |
Ref 0.77 (0.41–1.47) | 0.430 |
| Histological grade: WD MD + PD |
Ref 1.11 (0.71–1.73) | 0.640 |
| Overall response: CR + PR NR |
Ref 1.28 (0.69–2.36) | 0.429 |
| p53 expression: Low (≤25 %) High (>25 %) |
Ref 0.56 (0.35–0.89) | 0.014 |
Odds ratio were calculated with respect to ref group.