. 2015 Jul 15;16(9):1269–1280. doi: 10.1080/15384047.2015.1070985

Table 7.

Association of demographic, clinico-pathological characteristics and EGFR expression levels (%) with QOL domains at baseline, after 1 month of treatment and last follow up using multivariate regression analysis (n = 120)

	Baseline (n = 120) Standardized regression coefficient (b)					After 1 month of treatment (n = 120) Standardized regression coefficient (b)					Last follow up (n = 120) Standardized regression coefficient (b)
Predictors	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern
Age	−0.013^ns	0.066^ns	−0.045^ns	0.026^ns	−0.022^ns	0.103^ns	0.090^ns	−0.005^ns	0.086^ns	−0.026^ns	0.102^ns	0.056^ns	0.049^ns	0.106^ns	0.167^*
Sex	0.185^*	0.226^*	0.034^ns	0.149^ns	0.192^*	0.236^**	0.171^ns	0.105^ns	0.135^ns	0.199^**	0.036^ns	0.062^ns	−0.041^ns	0.041^ns	0.100^ns
Performance status	0.022^ns	0.037^ns	0.121^ns	0.141^ns	0.097^ns	0.089^ns	0.027^ns	0.121^ns	0.121^ns	0.081^ns	0.072^ns	0.071^ns	0.116^ns	0.070^ns	0.053^ns
Lesion site	0.017^ns	0.038^ns	0.056^ns	0.025^ns	0.029^ns	−0.030^ns	0.024^ns	0.037^ns	−0.029^ns	−0.041^ns	0.025^ns	−0.052^ns	0.006^ns	0.009^ns	0.086^ns
Tumor size	0.010^ns	−0.008^ns	−0.041^ns	0.105^ns	−0.022^ns	−0.089^ns	−0.028^ns	−0.017^ns	−0.064^ns	−0.052^ns	−0.104^ns	−0.042^ns	−0.235^ns	−0.077^ns	0.047^ns
Node metastasis	−0.033^ns	0.030^ns	−0.086^ns	0.081^ns	0.147^ns	−0.062^ns	−0.039^ns	0.039^ns	−0.040^ns	−0.013^ns	−0.120^ns	−0.093^ns	−0.093^ns	−0.153^*	−0.141^*
Stage	0.034^ns	0.033^ns	0.159^ns	−0.088^ns	−0.012^ns	−0.023^ns	0.041^ns	0.077^ns	0.057^ns	−0.069^ns	0.073^ns	0.109^ns	0.333^*	0.108^ns	−0.079^ns
Histological grade	0.218^*	0.086^ns	0.065^ns	0.017^ns	−0.001^ns	0.092^ns	0.098^ns	−0.051^ns	0.053^ns	0.018^ns	0.032^ns	0.031^ns	−0.051^ns	0.056^ns	−0.024^ns
Overall response	NA					−0.233^**	−0.203^*	−0.269^**	−0.067^ns	−0.304^***	−0.289^**	−0.292^**	−0.272^**	−0.385^***	−0.596^***
EGFR	−0.457^***	−0.364^***	−0.569^***	−0.347^***	−0.424^***	−0.333^***	−0.409^***	−0.400^***	−0.429^***	−0.512^***	−0.403^***	−0.399^***	−0.384^***	−0.352^***	−0.216^**

^ns

- P > 0.05,

- P < 0.05,

^**

- P < 0.01,

^***

- P < 0.001.

NA: Overall response not included in the analysis as it is not available at baseline.

Standardized regression coefficient (b): − sign indicates negative (inverse) effect, + sign indicates positive (direct) effect.