. 2015 Jul 15;16(9):1269–1280. doi: 10.1080/15384047.2015.1070985

Table 8.

Association of demographic, clinico-pathological characteristics and p53 expression levels (%) with QOL domains at baseline, after 1 month of treatment and last follow up using multivariate regression analysis (n = 120)

	Baseline (n = 120) Standardized regression coefficient (b)					After 1 month of treatment (n = 120) Standardized regression coefficient (b)					Last follow up (n = 120) Standardized regression coefficient (b)
Predictors	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern	Physical well being	Social/family well being	Emotional well being	Functional well being	Additional concern
Age	0.004^ns	0.078^ns	−0.020^ns	0.040^ns	−0.002^ns	0.112^ns	0.102^ns	0.013^ns	0.100^ns	−0.003^ns	0.115^ns	0.067^ns	0.066^ns	0.115^*	0.173^**
Sex	0.100^ns	0.158^*	−0.058^ns	0.089^ns	0.129^ns	0.142^ns	0.061^ns	0.026^ns	0.028^ns	0.101^ns	−0.065^ns	−0.044^ns	−0.115^ns	−0.055^ns	0.044^ns
Performance status	−0.069^ns	−0.037^ns	0.041^ns	0.083^ns	0.049^ns	0.047^ns	−0.021^ns	0.095^ns	0.076^ns	0.049^ns	0.030^ns	0.025^ns	0.092^ns	0.028^ns	0.029^ns
Lesion site	0.009^ns	0.031^ns	0.044^ns	0.018^ns	0.020^ns	−0.034^ns	0.018^ns	0.030^ns	−0.035^ns	−0.051^ns	0.019^ns	−0.058^ns	−0.001^ns	0.004^ns	0.083^ns
Tumor size	0.059^ns	0.033^ns	−0.012^ns	0.132^ns	−0.013^ns	−0.074^ns	−0.013^ns	−0.023^ns	−0.055^ns	−0.063^ns	−0.094^ns	−0.029^ns	−0.242^*	−0.063^ns	0.054^ns
Node metastasis	0.031^ns	0.083^ns	−0.049^ns	0.116^ns	0.159^ns	−0.048^ns	−0.026^ns	0.026^ns	−0.034^ns	−0.033^ns	−0.113^ns	−0.082^ns	−0.107^ns	−0.140^*	−0.136^*
Stage	−0.080^ns	−0.059^ns	0.036^ns	−0.169^ns	−0.097^ns	−0.095^ns	−0.045^ns	0.006^ns	−0.030^ns	−0.159^ns	−0.009^ns	0.026^ns	0.265^*	0.033^ns	−0.123^ns
Histological grade	0.083^ns	−0.024^ns	−0.062^ns	−0.072^ns	−0.080^ns	0.022^ns	0.017^ns	−0.103^ns	−0.025^ns	−0.047^ns	−0.041^ns	−0.047^ns	−0.100^ns	−0.015^ns	−0.065^ns
Overall response	NA					−0.087^ns	−0.035^ns	−0.176^*	0.089^ns	−0.191^**	−0.140^*	−0.131^*	−0.186^*	−0.236^***	−0.512^***
p53	−0.856^***	−0.693^***	−0.883^***	−0.591^***	−0.588^***	−0.629^***	−0.741^***	−0.543^***	−0.725^***	−0.677^***	−0.686^***	−0.716^***	−0.510^***	−0.650^***	−0.378^**

^ns

- P > 0.05,

- P < 0.05,

^**

- P < 0.01,

^***

- P < 0 .001.

NA: Overall response not included in the analysis as it is not available at baseline.

Standardized regression coefficient (b): − sign indicates negative (inverse) effect, + sign indicates positive (direct) effect.