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. 2015 May 11;16(7):1071–1079. doi: 10.1080/15384047.2015.1046024

Figure 5.

Figure 5.

Restoration of mucin 1 expression reverses miR-145-suppressed proliferation, migration and invasion. (A) CCK-8 assays showed that mucin 1 promoted the proliferation of A549-miR-145 and NCI-H520-miR-145 cells compared with mock groups. (B) The colony-forming abilities of A549-miR-145 and NCI-H520-miR-145 cells transfected with the mucin 1 vector were promoted compared with cells transfected with the control vector. (C) Transwell migration assays and matrigel invasion assays indicated that mucin 1 increased the migration and invasion abilities of A549-miR145 and NCI-H520-miR145 cells.