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The role of IFNβ in the clearance of senescent cells in vitro. (A). Scheme of the experiment to determine the role of IFNβ in the clearance of senescent cells in vitro. (B). Growing (MRC5, p37) or senescent cells (MRC5, p66; HGPS or WS cells) were pre-treated with IFNβ neutralizing antibody (or control IgG) for 12 h, washed and incubated with natural killer YT cells overnight. Percentage of clearance of indicated cells is depicted. ***p < 0.001.
