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. 2015 Mar 11;7(2):311–320. doi: 10.1080/19420862.2015.1007813

Figure 4.

Figure 4.

Human macrophages induce DARA-dependent phagocytosis of BL and MM cell lines. Phagocytosis of BL cells (left panel) or MM cells (right panel) by human mφ in the presence of 6.7 nM mAb, E:T ratio of 2:1. (A) Percentage of double positive (DP) mφ characterized as CD11b+calcein+target Ag. (B) Percentage of eliminated target cells calculated from the number of remaining CD11b- cells as described in Materials & Methods. Each bar shows mean ± SEM, results from a representative experiment (n = 3) (**p < 0.01, ***p < 0.001, ****p < 0.0001 Bonferroni's multiple comparison test).