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. 2015 Mar 25;16(5):662–670. doi: 10.1080/15384047.2015.1026507

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

© Edward J Wyluda, Jihua Cheng, Todd D Schell, Jeremy S Haley, Carol Mallon, Rogerio I Neves, Gavin Robertson, Jeffrey Sivik, Heath Mackley, Giampaolo Talamo, and Joseph J Drabick

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — Patient 3. PET/CT in August 2013 (left, prior to BRAF inhibitor therapy) showed intensely FDG avid lymph nodes post ipilimumab which were biopsy confirmed metastatic melanoma. PET/CT in November 2013(right, after trametinib) showed the previously described intensely FDG avid lymph nodes and nodules had entirely resolved. The skin nodules on his scalp also resolved. The trametinib was gradually weaned and stopped by 5/14. He has remained in complete remission to date off therapy.