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. 2015 Apr 18;16(5):770–779. doi: 10.1080/15384047.2015.1026477

Table 1.

CI values of DHA at concentrations applied in combination with CQ in Hela and HCT116 cells

Hela
HCT116
DHA (μM) CQ (μM) Combination index DHA (μM) CQ (μM) Combination index
2.5 1.25 0.899 2.5 1.25 0.487
5 2.5 0.538 5 2.5 0.446
10 5 0.315 10 5 0.544
20 10 0.335 20 10 0.485
40 20 0.351 40 20 0.289
80 40 0.396 80 40 0.126

A CI less than 0.90 indicates synergism; 0.10, very strong synergism; 0.10–0.30, strong synergism; 0.30–0.70, synergism; 0.70–0.85, moderate synergism; 0.85–0.9, slight synergism; 0.90–1.10, additive; and more than 1.10, antagonism.