Table 6.

ED₅₀ and ED₈₀ for ABT‑981 to neutralize human or cynomolgus IL‑1α or IL‑1β

	Human IL-1α		Cynomolgus IL-1α		Human IL-1β		Cynomolgus IL-1β
	ED50 (mg/kg)	ED80 (mg/kg)	ED50 (mg/kg)	ED80 (mg/kg)	ED50 (mg/kg)	ED80 (mg/kg)	ED50 (mg/kg)	ED80 (mg/kg)
Expt #1	0.007	0.17	5.2	16.15	0.02	0.27	0.002	0.098
Expt #2	0.002	0.04	7.7	20.16	0.012	0.32	0.006	0.11
Average	0.005	0.104	6.5	18.2	0.016	0.28	0.004	0.094