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. 2014 Nov 18;9(11):1461–1472. doi: 10.4161/15592294.2014.971608

Table 1.

Numbers of CpG sites associated with significant changes in methylation during TGF-β -induced EMT in SKOV3 cellsa

  Increased Methylation
Decreased Methylation
Comparisons Numbers Δβ Rangeb Numbers Δβ Rangeb
48 h vs. Control 351 0.007–0.168 117 0.010–0.151
120 h vs. Control 344 0.007–0.145 46 0.009–0.130
120 h + 48 h off vs. Control 35 0.026–0.297 45 0.020–0.317
Common changes at 48 and 120 h 130 - 30 -

aCells were treated with TGF-β (5 ng/ml) for 48 h, 120 h, or 120 h followed by TGF-β removal for 48 h (120 h + 48 h off). Significant changes: P < 0 .01 (ANOVA) and FDR < 0 .05.

bΔβ = Difference in average β-values between treatments per CpG site.