Table 1.
TNF locus | Allele | Size (bp) | Controls (n = 164) | CAG (n = 53) | Gastric adenocarcinoma (n = 56) | P value |
TNFa | a1 | 97 | 0.0183 | 0.0094 | 0.0089 | |
a2 | 99 | 0.1583 | 0.1698 | 0.2054 | ||
a3 | 101 | 0 | 0.0094 | 0.0268 | ||
a4 | 103 | 0.0061 | 0.0094 | 0.0178 | ||
a5 | 105 | 0.0396 | 0.0378 | 0.0089 | ||
a6 | 107 | 0.3811 | 0.3585 | 0.3928 | ||
a7 | 109 | 0.0793 | 0.0378 | 0.0536 | ||
a8 | 111 | 0.0061 | 0.0094 | 0 | ||
a9 | 113 | 0.0335 | 0.0566 | 0.0152 | ||
a10 | 115 | 0.1189 | 0.1981* | 0.1161 | 0.04 | |
a11 | 117 | 0.0945 | 0.066 | 0.0803 | ||
a12 | 119 | 0.0091 | 0 | 0 | ||
a13 | 121 | 0.0549 | 0.0378 | 0.0152 | ||
TNFb | b1 | 125 | 0.1006 | 0.0755 | 0.1339 | |
b2 | 126 | 0 | 0 | 0 | ||
b3 | 127 | 0.1128 | 0.0943 | 0.0536 | ||
b4 | 128 | 0.3293 | 0.3585 | 0.3482 | ||
b5 | 129 | 0.4512 | 0.4717 | 0.4643 | ||
b6 | 130 | 0 | 0 | 0 | ||
b7 | 131 | 0.0061 | 0 | 0 | ||
TNFc | c1 | 159 | 0.2104 | 0.7264 | 0.7679 | |
c2 | 161 | 0.7896 | 0.2736 | 0.2321 | ||
TNFd | d1 | 124 | 0.0061 | 0.0094 | 0 | |
d2 | 126 | 0.0548 | 0.0755 | 0.0536 | ||
d3 | 128 | 0.0457 | 0.0566 | 0.0446 | ||
d4 | 130 | 0.3537 | 0.3774 | 0.3393 | ||
d5 | 132 | 0.1341 | 0.1226 | 0.1786 | ||
d6 | 134 | 0.3018 | 0.2925 | 0.2857 | ||
d7 | 136 | 0 | 0 | 0 | ||
d8 | 138 | 0.1037 | 0.066 | 0.0982 | ||
TNFe | e1 | 99 | 0.064 | 0.0755 | 0 | |
e3 | 103 | 0.811 | 0.8302 | 0.7768 | ||
e4 | 105 | 0.1159 | 0.066 | 0.125 | ||
TNF-α 308 | 1 | 0.9329 | 0.9434 | 0.9732 | ||
2 | 0.0671 | 0.0566 | 0.0268 | |||
TNF-β Nco1 | 1 | 0.4817 | 0.4528 | 0.4464 | ||
2 | 0.5183 | 0.5472 | 0.5536 | |||
TNF- β AspH1 | 1 | 0.3079 | 0.3302 | 0.3571 | ||
2 | 0.6921 | 0.6698 | 0.6429 |