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Effects of estradiol metabolites on function of HSCs proliferation (A), HA (B) and C IV (C) secretion in HSCs, effects of 10-7 mol/L estradiol metabolites on α-SMA expression (D) of HSCs. Values for each point represent mean ± SD from 5 separate experiments, aP < 0.05 vs control, dP < 0.05 vs 10-7 mol/L β-Est.
