Table 1.

Methylated miRNAs and their role in cancer

miRNA	Cancer activity	Ref
miR-145	Involved in cell pluripotency	61
miR-193	Controls cell differentiation and cell growth in acute myeloid leukemia	62
miR-199a	Controls the expression of genes associated with tumor progression in gastric, ovarian and testicular tumors	63
miR-335	Its hypermethylated phenotype has been associated with metastases in breast cancer	64
miR-1–133a cluster	Modulates metastases in colorectal cancer by repressing TAGLN2	65
miR-200 family	Downregulated in colorectal and breast tumors, favoring epithelial–mesenchymal transition (EMT) phenotypes	66