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Affinity of Hu 15C1 and C2E3 for TLR4
| Antibody | kon (105M−1s−1) ± SD | koff (10−4s−1) ±SD | KD (10−9M) ± SD | KD (fold gain)1 | Relative affinity2 |
|---|---|---|---|---|---|
| Hu 15C1 | 2.26 ± 0.07 | 6.85 ± 0.06 | 3.03 ± 0.07 | 1 | 1 |
| C2E3 | 4.76 ± 0.06 | 0.39 ± 0.01 | 0.082 ± 0.003 | 37 | 39 |
1Affinity improvement are reported as fold gain over Hu 15C1.
2See Material and Methods.
