Table 2.

Association of expression modules with tumor grade, tumor size, and survival in discovery set

		Correlation with tumor grade		Correlation with tumor size		Association with DMFS (n = 87)
Modules	Gene count	R	p-value	R	p-value	HR	p-value	95% CI
Blue	429	−0.23	5.1 × 10–2	0.09	4.2 × 10–1	0.63	2.3 × 10–1	0.30–1.34
Black	64	−0.35	3.0 × 10–2	−0.21	5.2 × 10–2	0.81	5.7 × 10–1	0.38–1.70
Green	139	−0.30	1.1 × 10–2	−0.05	6.7 × 10–1	0.59	1.7 × 10–1	0.28–1.25
Magenta	37	0.31	8.0 × 10–3	0.15	1.5 × 10–1	2.50	2.4 × 10–2	1.13–5.53
Turquoise	507	0.63	5.4 × 10–9	0.26	2.6 × 10–2	2.25	4.1 × 10–2	1.03–4.88
Pink	46	0.18	1.5 ×10–1	−0.01	9.2 × 10–1	1.30	4.9 × 10–1	0.62–2.75
Brown	395	0.05	7.1 × 10–1	0.18	9.1 × 10–2	0.57	1.5 × 10–1	0.27–1.22
Red	79	0.22	6.3 × 10–2	0.26	1.5 × 10–2	0.62	2.2 × 10–1	0.29–1.33
Yellow	358	0.30	1.1 × 10–2	0.28	8.0 × 10–3	1.12	7.6 × 10–1	0.53–2.37

CI, confidence interval. Distant metastasis free survival (DMFS).

Hazard ratios (HRs), 95% confidence intervals (CI), and p-values were calculated using Cox proportional hazards regression analysis after grouped the breast cancer patients by the median of module eigengenes level.