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. 2015 May 27;7(4):693–706. doi: 10.1080/19420862.2015.1046648

Figure 2.

Figure 2.

Human identity of camelid IGVL germline families and their corresponding members. Similarity of each of the camelid germline families to their human counterparts is represented by a set of alignments based on the canonical folds of CDR1-2 and the % identity of their corresponding frameworks (FRs). The percentage of identity (%Identity) corresponds to identical amino acids of the V gene framework families (FR1+FR2+FR3) shared by each of the Camelus ferus (camel), Lama pacos (alpaca) and Lama glama (llama) with human IGV reference counterparts (Ref). The % identity is illustrated only for potentially functional genes. Canonical folds of CDR1-2 are indicated between parentheses. Stop codons are indicated by a star (*), missing or incomplete amino acid sequences are indicated by a space, and out of frame parts of V gene sequences are indicated by a dash (−).