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Apparent solubility of MAB 1 and variants measured using the PEG precipitation method*
| Antibody name | Apparent solubility score (%PEG) |
|---|---|
| MAB 1 Control | 10.3 ± 0.1 |
| M1 | 8.9 ± 0.1 |
| M2 | 8.5 ± 0.1 |
| M3 | 11.8 ± 0.1 |
| M4 | 8.6 ± 0.1 |
| M6 | 11.3 ± 0.1 |
| RefmAb | 19.5 ± 0.5 |
MAB 1 Control is the parent MAB 1 produced at Pfizer using CHO cells. RefmAb is the same antibody as in Table 1A and 1C.
