Table 1.
HPV | SMAD4 | SMAD4.Low | SMAD4.High |
---|---|---|---|
HPV+ | Homozygous Deletion | 0 | 0 |
Nonsense Mutation | 0 | 0 | |
Missense / Silent Mutation | 0 | 1 (p.P298S) | |
WT | 3 | 32 | |
HPV- | Homozygous Deletion | 13 | 0 |
Nonsense Mutation | 2 (p.S242*; p.Q461*) | 0 | |
Missense / Silent Mutation | 2 (p.W99C; p.R361H) | 2 (p.P544L; p.K46K) | |
WT | 122 | 102 |