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Effects of PRIMA-1Met in combination with current WM therapeutics. (A) Synergism was assessed by combination index (CI) analysis for dexamethasone and RIMA-1 after 72hrs, CI = 0.63. (B)RIMA-1met has synergistic effects with bortezomib velcade on BCWM-1 cells, 72hrs, CI = 0.85. Error bars = SEM, ** P = <0.01
