3-Cl-AHPC decreased hTERT activity in pancreatic cancer cells. (A, B) 3-Cl-AHPC decreased hTERT mRNA and protein expression. (C, D) 3-Cl-AHPC decreased telomerase activities in cells. Error bars represent the mean of 3 separate determinations ± SD. *, **, and *** (<0 .05, <0 .01 and <0 .001) were significantly different in the treated samples compared to control using the t-Test.