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. 2015 Jul 7;104:918–928. doi: 10.1007/s00392-015-0888-2

Table 8.

Relevant changes of the criteria of the German Society of Cardiology for Chest Pain Unit: 2008 to 2014

Criterium 2008 Minimal requirements Additional recommendations 2014 Minimal requirements Additional recommendations
Rhythm monitoring At each bed ST-segment monitoring At each bed ST-segment monitoring omitted
Exercise testing, CT-scan coronary arteries Available within three business days; an appointment must be given upon discharge and entered in the discharge letter; when possible, in cooperation with outpatient clinics Located in the CPU Available within three business days; an appointment must be given upon discharge and entered in the discharge letter When possible, in cooperation with outpatient clinics
Laboratory values (cardiac) Troponin T or I CK, CK-MB, BNP, nt-proBNP, multimarker, Myoglobin Troponin T or I hsTroponin T, BNP, Nt-proBNP, Copeptin (new) (multimarker and myoglobin omitted)
Timing of determination of laboratory values 0 + 6 to 12 h after admission 0–3–6 h, additional sampling after another chest pain event 0 + 6 and up to 9 h after admission 0–3 h in case of use of hsTroponin T, additional sampling after another Chest Pain Attack, 0–1 (2) h in case of hsTn assays in patients with low risk
Laboratory values (general) Electrolytes, creatinine, blood count, CRP, coagulation status Additional diagnostics, thyroid function tests (TSH), (repeated) D-Dimer if clinically indicated Electrolytes, creatinine, blood count, CRP, coagulation status, D-Dimer if clinically indicated (now minimal requirement) Additional diagnostics when indicated, thyroid function tests (TSH)
TTE All unstable patients, based on clinical indications. Available on 365 days/24 h All patients with ACS or other clinical indications—365 days/24 h availability
Risk stratification (new) GRACE-score at admission Additional risk scores
Algorithms for patients` treatment STEMI (two different algorithms for patients with in-hospital and pre-hospital diagnosis), NSTEMI, unstable angina pectoris, stable angina pectoris, hypertensive crisis, acute lung embolism, acute aortic dissection, cardiogenic shock, resuscitation Additional algorithms STEMI (two different algorithms for patients with in-hospital and pre-hospital diagnosis), NSTEMI, unstable angina pectoris, stable angina pectoris, hypertensive crisis, acute lung embolism, acute aortic dissection, cardiogenic shock, resuscitation, ICD discharge, SM-malfunction, atrial fibrillation (new) Additional algorithms
Catheterization laboratory accessibility Every STEMI within 90–120 min, every NSTEMI/UA with moderate to high risk 48–72 h Every STEMI within 90–120 min (contact-to-balloon time), patients with NSTEMI/UA with very high risk: immediately; with high risk (GRACE > 140) within 24 h; with low risk: within 72 h, or according to most current guidelines
Emergency services Integration in the regional plan for ACS Integration in the existing emergency system Integrated structures for the therapy of ACS at a regional and nationwide
Catheterization laboratory Available 365 days/24 h, transfer time <15 min, with at least four interventional cardiologists Available 365 days/24 h, transfer time <15 min (the criterion of at least four cardiologists is deleted)
Additional cooperations Gastroenterology, heart surgery, outpatient clinics Psychosomatic medicine Heart surgery, outpatient clinics, gastroenterology is omitted Other disciplines
Psychosomatic medicine is omitted
Nursing staff Presence: 365 days/24 h Intensive care unit training Special CPU training Accredited training as Nurse expert (Chest Pain Unit), intensive care unit training
Quality control Feedback mechanisms for the assessment of the quality of the diagnostic and therapy Participation in the CPU-registry

Changes are highlighted in italic