Table 1.
Demographic, clinical and genetic data in patients with primary hypertension and control group
| Variable | Control group, N = 83 (n = 40 boys) | PH patient group, N = 126 (n = 95 boys) | p |
|---|---|---|---|
| Age (years) | 12 (5–18) | 15 (5–18) | ns |
| Birth weight (g) | 3520 (1960–4400) | 3355 (1410–5250) | 0.06 |
| BMI (kg/m2) | 19.2 ± 3.9 | 24.8 ± 4.5 | <0.001 |
| BMI SDS | 0.27 ± 1.13 | 1.75 ± 1.7 | <0.001 |
| WC (cm) | n.a. | 84 (53–111) | - |
| WC SDS | n.a. | 1.62 (−2.03 to 6.12) | - |
| cIMT (mm) | 0.40 (0.31–0.53) | 0.43 (0.34–0.63) | <0.001 |
| cIMT SDS | 0.50 (−2.27 to 3.46) | 0.97 (−1.37 to 7.83) | <0.001 |
| LVMi (g/m2.7) | n.a | 35.3 (19.1–62.3) | - |
| Number of patients with GT and TT alleles | 45 (54.2 %) | 66 (52.4 %) | ns |
| Number of patients with TT alleles | 8 (9.6 %) | 13 ( 10.3 %) | ns |
Data are presented as the mean ± standard deviation (SD), as the median with the range in parenthesis or as a number with the percentage in parenthesis, as appropriate
PH Primary hypertension, BMI body mass index, cIMT carotid intima-media thickness, LVMi left ventricular mass index, SDS standard deviation score, n.a. not assessed, GT carriers of G894 and T894 allele, TT T894 homozygotes, WC waist circumference