Table 1. PSC induction efficiency by double KD of Dmrt1 and Trp53.

Cell type	Number of experiments	Number of infected cells (× 104)	Number of PSC colonies /105 cells	Number of PSC colonies /105 germ cellsa)
8.5 dpc	4	19.3 ± 0.8	0.3 ± 0.2	28.1 ± 16.3
10.5 dpc	4	19.0	0.2 ± 0.2	24.9 ± 17.0
12.5 dpc	6	32.1 ± 5.5	9.7 ± 4.7	123.9 ± 59.8
15.5 dpc	5	50.0	0	0
18.5 dpc	4	50.0	0	0
8–10 dpp	10	50.0	0	0
GSC	10	50.0	0.4 ± 0.3	0.4 ± 0.3

Values are shown as the mean ± SEM. ^a) These values for fresh germ cells were normalized by the number of POU5F1-positive (8.5 to 12.5 dpc) or TRA98-positive (15.5 dpc to 8–10 dpp) cells, as determined by immunostaining (Supplementary Fig. 1B: online only).