Voltage-dependent rates in model M2. Rates were fitted across voltages from −30 to +50 mV, using MIL as implemented in QuB. The graphs of the three rates that appear voltage sensitive (C2 > C1, C3 > C1, and O1 > S) are shown in (A), (B), and (C), respectively. Individual recordings at each voltage (black circles) are shown and the horizontal black bars are the mean rates at each voltage (SE). The global fit, where all recordings obtained under a given condition were fitted simultaneously (also in QuB), are plotted as red bars. At −30 mV, only four recordings were available with openings. The number of openings was insufficient to fit rates for individual recordings, therefore global fits only are shown at −30 mV. The following number of recordings were used at each voltage: −30 mV (4), 10 mV (4), 20 mV (9), 30 mV (15), 40 mV (8), and 50 mV (5). To see this figure in color, go online.