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. 2015 Jul 21;109(2):265–276. doi: 10.1016/j.bpj.2015.06.020

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© 2015 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Contribution of the full open and subconductance states to the overall current flowing through the channel. The relationship between mean current and voltage is shown for the full open state (A), and for openings to any subconductance level (B). Mean current contributions due to full and subconductance open states for individual experiments are plotted as open circles. Mean values ± SE are shown (n = 8 (−30 mV), 7 (10 mV), 12 (20 mV), 17 (30 mV), 10 (40 mV), and 4 (50 mV)). Percentage contributions of the full open and combined subconductance states to the total current were then computed for each experiment and were averaged across individual experiments at the various holding potentials (C). To see this figure in color, go online.